Zhou F, et al. - In patients who underwent cervical disc replacement (CDR), the prevalence, clinical significance, ramifications, and possible etiology of postoperative bone formation at the index level was examined, with a minimum of 5 years of follow-up. Post-CDR, a relatively high long-term incidence of postoperative bone formation was reported, with no adverse impact on patient outcomes. Higher rates of postoperative ossification were reported in patients with more severe preoperative spondylosis. This indicates that postoperative ossification at the CDR segment is likely one of progressive bone formation in individuals already predisposed to forming bone rather than one of alleged heterotopic ossification as a consequence of the surgery.