Wang H, et al. - Whether and how linc00152 holds clinical value as a prognostic indicator in malignant tumors was clarified via a synthetic analysis of articles gathered from various electronic databases, including PubMed, Web of Science, Medline, OVID, and Embase (up to February 13, 2018). Researchers carried out a meta-analysis of nine original studies, with 808 patients. Using a random-effects model, they found a significant positive link between the high expression level of linc00152 and lymph node metastasis and negative link with low-grade cancer, while with tumor recurrence by fixed-effects model as the low heterogeneity. In human solid cancers, a positive association of Linc00152 overexpression with poor overall survival and poor disease-free survival was revealed via the use of the fixed-effects model. They also identified statistically significant links with cancer type, sample size, and follow-up time. Findings revealed the potential value of linc00152 as a new biomarker of lymph node metastasis and prognosis in human cancer.