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Prognostic value of visit-to-visit systolic blood pressure variability related to diabetic kidney disease among patients with type 2 diabetes

Journal of Hypertension Jun 05, 2019

Yu ZB, et al. - Using a retrospective cohort design, a total of 12,630 type 2 diabetes mellitus (T2DM) patients were examined in China to assess the influence of blood pressure visit-to-visit variability (VVV) on the risk of diabetic nephropathy as well as its predictive ability. Researchers evaluated VVV of SBP as standard deviation, coefficient of variation and variation independent of mean of the blood pressure readings during the measurement period. Across the quartiles of VVV SBP, a dose–response link was evident. They noted significantly improved risk prediction for diabetic kidney disease (DKD) was enabled with the addition of SD SBP. Overall, VVV of SBP conferred a significant risk for DKD among T2DM patients in addition to mean and max BP values, offering additional significant predictive information.

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