Park SH, et al. - Researchers analyzed the serum levels of S100 calcium-binding protein B (S100B), neuron-specific enolase (NSE), and interleukin (IL)-6 in pediatric patients with TBI (traumatic brain injury), and determined their relationship with clinical outcome. Findings revealed lowering of serum levels of S100B, NSE, and IL-6 1-week after injury. At admission, the serum levels of S100B and NSE were related to the initial Glasgow Coma Scale scores, and 1 week after the TBI, these levels showed correlation with 6-month GOS scores. Thus, indicating the value of serial measurements of serum S100B and NSE, but not IL-6, in assessing brain damage and clinical outcome of pediatric TBI patients.