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Prognostic value of subcutaneous adipose tissue volume in hepatocellular carcinoma treated with transcatheter intra-arterial therapy

Cancer Management and Research Aug 02, 2018

Kobayashi T, et al. - In this retrospective analysis, researchers investigated whether body composition measurements, such as skeletal muscle and visceral and subcutaneous adipose tissues (VAT and SAT, respectively) has a prognostic significance in hepatocellular carcinoma (HCC) patients treated with transcatheter intra-arterial therapies. They assessed 100 HCC patients treated with transcatheter intra-arterial therapies between 2005 and 2015. They performed univariate and multivariate analyses using Cox proportional hazards models to evaluate the prognostic significance. They found an association between high SAT volume and better survival outcomes. The suggested independent prognostic factors for overall survival included SAT index (SATI), serum albumin, serum alpha-fetoprotein, and Modified Response Evaluation Criteria in Solid Tumors assessment.

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