Lee H, Kim HK, Kang D, et al. - Whether a six-minute walk test (6MWT) has a role in predicting postoperative cardiopulmonary complications among non-small cell lung cancer (NSCLC) patients who had a lobectomy and showed moderately reduced lung function, was investigated in this study utilizing data from a prospective cohort investigation named Coordinate Approach To Cancer patient’s Health for Lung Cancer (CATCH – LUNG). Cases treated with lobectomy for NSCLC and with ECOG status 0 or 1 were examined. Two groups of patients were defined based on predicted postoperative pulmonary function (low-risk group or moderate-risk group). Further categorization of each group was done into short-distance (< 400m) or long-distance (≥ 400m) groups by a six-minute walk distance. The incidence of postoperative cardiopulmonary complications developing within the first 30 days after surgery was the main endpoint. While a greater risk of postoperative cardiopulmonary complications was observed in NSCLC patients with moderate-risk/short-distance, findings revealed the feasibility of undergoing lobectomy among NSCLC patients with moderate-risk/long-distance vs those with low-risk/long-distance. In the detection of optimal candidates for lung resection surgery of NSCLC, additional information could be gained via 6MWT.