Shukla M, et al. - The prognostic value of right ventricular (RV) strain, using 2-dimensional speckle-tracking echocardiography (STE), for the clinical endpoint of all-cause mortality was assessed in patients with pulmonary hypertension (PH). Relevant publications identified from the MEDLINE, Embase and Cochrane Library databases were analyzed. The pooled free wall RV strain was noted to be -16.2%, and the global (free wall and septum) RV strain was -14.5%. According to six publications, 3.67 was the pooled unadjusted hazard ratio for a binary cut-off RV strain value for the primary outcome, while 1.14 was reported as the pooled unadjusted hazard ratio of RV strain as a continuous variable (per 1% change). Overall, within a large and mixed population of PH patients, the prognostic utility of RV strain, as assessed using 2-dimensional STE, was demonstrated.