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Prognostic value of minichromosome maintenance mRNA expression in early-stage pancreatic ductal adenocarcinoma patients after pancreaticoduodenectomy

Cancer Management and Research Sep 13, 2018

Liao X, et al. - By utilizing the RNA-sequencing dataset from The Cancer Genome Atlas (TCGA), researchers assessed the possible predictive value of minichromosome maintenance (MCM) genes in patients with early-stage pancreatic ductal adenocarcinoma (PDAC) following pancreaticoduodenectomy. The findings from the present study suggested that MCM2–7 were upregulated in pancreatic cancer tumor tissues, and mRNA expression of MCM4 could be an independent prognostic indicator in these patients.

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