Lampert J, Miller M, Halperin JL, et al. - Dynamic QRS amplitude diminution is identified to have a strong independent predictive value for death over the course of COVID-19 infection as well as influenza infection.

• A composite of QRS amplitude < 5mm or < 10 mm in the limb or precordial leads, respectively, or a ≥ 50% reduction in QRS amplitude on follow-up ECG during hospitalization was defined as low QRS complex amplitude (LoQRS).

• Patients with COVID-19 more frequently had LoQRS relative to those with influenza (24.3% vs 11.7%), and its high prevalence was observed in patients who died vs survived with either COVID-19 (48.1% vs 10.2%) or influenza (38.9% vs 9.9%).

• In COVID-19, the median time to death was 52 hours from the first ECG with LoQRS.