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Prognostic value of different maternal obesity phenotypes in predicting offspring obesity in a family-based cohort study

BMC Public Health May 12, 2021

Jalali-Farahani S, Amiri P, Lashkari B, et al. - In a large cohort of the Tehranian population, researchers sought to explore the connection between maternal obesity phenotypes and incidence of obesity in their offspring. This investigation was carried out within the framework of the Tehran Lipid and Glucose Study. In total, 2,151 non-obese children who had complete parental information were followed for incidence of obesity over a mean of 148.7 ± 34.7 months. According to this longitudinal study, except for the normal weight/dysmetabolic phenotype, all maternal obesity phenotypes had significant prognostic values for offspring obesity incidence, with the obese/dysmetabolic phenotype having the highest risk. This research provides useful information for determining the first-line target groups for obesity prevention strategies in children.

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