Nam K, Hur J, Han K, et al. - Among 762 ischemic stroke patients with risk factors for coronary artery disease (CAD) and without chest pain, researchers assessed prognostic value and additional risk stratification benefits of CAD-reporting and data system (CAD-RADS) vs coronary artery calcium scores (CACS) and CAD extent classifications. Major adverse cardiovascular events (MACEs), defined as cardiovascular death, nonfatal myocardial infarction, unstable angina needing hospitalization, and revascularization, were assessed as the primary endpoint. Participants were followed for a mean duration of 3.36 years, during which, 67 MACEs were documented. Overall, there were762 patients. The risk of future MACEs was independently stratified by CACS, CAD extent classification, and CAD-RADS scores. In this study, the prognostic value of CAD-RADS for future MACEs, as well as its ability to offer better risk discrimination compared with CACS alone was shown.