Alis D, et al. - Through this study, researchers sought to predict the overall survival of the patients who underwent Yttrium 90 radioembolization (⁹⁰Y-RE) for colorectal liver metastases (CLM) via diffusion-weighted imaging (DWI) with other well-established clinical and imaging parameters, along with, to compare the apparent diffusion coefficient (ADC) values of the lesions pre- and post-treatment. Response Evaluation Criteria in Solid Tumors (RECIST), hepatic tumor burden, Eastern Cooperative Oncology Group performance status (ECOG–PS) and the presence of extrahepatic metastases in predicting overall survival (OS) was assessed. Longer OS in CLM patients was associated with an increase in relative ADC_p or ADC_e values post ⁹⁰Y-RE treatment whereas to predict OS in CLM patients during the early post-interventional period after ⁹⁰Y-RE, DWI appeared as a valuable imaging biomarker.