Chae M, Jeon JH, Chung JH, et al. - Among patients with stage IA part-solid lung adenocarcinoma following sublobar resection, researchers evaluated the clinicopathologic implications of tumor spread through air spaces (STAS). This retrospective review involved 115 patients with stage IA part-solid adenocarcinoma who underwent wedge resection; STAS was detected in 20 (17.4%) of these. In patients with and without STAS, the 5-year freedom from recurrence rates were identified to be 62.4% and 97.9%, respectively, and the 5-year disease-free survival rates were estimated to be 58.5% and 97.9%, respectively. Based on these findings, experts concluded that STAS could serve as an essential prognostic factor in patients with stage IA part-solid lung adenocarcinoma following sublobar resection. Presence of STAS and a larger invasive component size were independent risk factors for recurrence, as seen in the multivariable analysis. Improvement in the outcome of patients with small part-solid nodules may be achieved, especially in cases accompanied by STAS, via effective preoperative assessment and postoperative surveillance.