Peng D, et al. - The prognostic significance of a novel index combining pre-operative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) in renal cell carcinoma (RCC) patients was determined. A close association between HALP and clinicopathologic features was noted. For RCC patients undergoing nephrectomies, HALP was an independent prognostic factor of cancer-specific survival. The prognosis of RCC can be accurately predicted by a nomogram based on HALP.