Okazaki E, et al. - From June 2007 to December 2015, 61 candidates were retrospectively evaluated using metabolic tumor volume (MTV) of the primary tumor and lymph nodes to study the utility of pretreatment positron emission tomography (PET) in advanced hypopharyngeal cancer. A significant association was reported between MTV of the primary tumor (MTV-T) and local control rate as well as overall survival (OS) on multivariate analysis. They also found that MTV of metastatic lymph nodes (MTV-N) was significantly associated with disease-specific survival and OS in subjects with lower MTV-T.