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Prognostic significance of pretreatment lymphocyte/monocyte ratio in retroperitoneal liposarcoma patients after radical resection

Cancer Management and Research Oct 26, 2018

Luo P, et al. - In patients with retroperitoneal liposarcoma (RPLS) after radical resection, researchers assessed the prognostic ability of pretreatment inflammatory biomarkers by analyzing data of 100 patients with RPLS who had radical resection between September 2004 and October 2010 at Fudan University Shanghai Cancer Center. Data reported that the median follow-up time was 53 months and the median disease-free survival (DFS) was 27 months and overall survival (OS) was 86 months. In RPLS patients following radical resection, pretreatment low lymphocyte/monocyte ratio (LMR) is a valuable prognostic marker. In univariate analysis, the low LMR group had significantly shorter DFS and OS vs the high LMR group. In multivariate analysis, low LMR was shown to be an independent negative prognostic factor for both DFS and OS.

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