Lin W, et al. - In this study involving 57 patients with primary mucinous ovarian carcinoma (MOC) and measured preoperative serum carcinoembryonic antigen (CEA), researchers assessed the prognostic significance of preoperative serum CEA. These patients had received treatment at Peking Union Medical College Hospital between June 1996 and September 2016. Ten patients (17.5%) had elevated (> 5.0 ng/mL) preoperative serum CEA, with a median serum CEA of 9.6 ng/mL (5.4–111.7 ng/mL). CEA was found to have a significant association with preoperative serum cancer antigen 125, surgical debulking status, and tumor stage. Significantly worse overall survival was observed in patients with elevated CEA vs those with normal CEA (5-year OS: 50.8% vs 91.9%, respectively); however, progression-free survival did not differ significantly between the two groups. In primary MOC, a strong correlation of elevated preoperative serum CEA with advanced stage was observed, suggestive of a poorer prognosis.