Patrão AS, et al. - Researchers assessed the importance of positive circumferential resection margin (CRM) in a homogeneous group of patients with esophageal or gastroesophageal junction (E/GEJ) adenocarcinoma treated with comparable perioperative chemotherapy. A retrospective study of 177 patients was performed; the majority of these (94.9%) received ECX (epirubicin, cisplatin, capecitabine), and all had clear proximal/distal resection margins. Outcomes suggest that CRM status had no independent prognostic influence, despite a correlation with poor outcome. The pattern of cancer relapse was not identified to be significantly influenced by CRM status.