Lee KH, Suh HY, Lee MW, et al. - Findings demonstrate that survival outcome in distant metastatic melanoma can be predicted with the help of epidermal growth factor receptor (EGFR) immunostaining.

• This is a retrospective study of 55 cases of distant metastatic melanoma, diagnostic tissues were assessed by immunohistochemistry for EGFR expression.

• A significant correlation was found between positive EGFR expression and the absence of ulceration.

• EGFR expression was significantly related to poor survival, under the conditions of male gender and primary cutaneous melanoma without ulceration or Breslow thickness ≤4.0 mm.