Zhou Z, et al. - In this retrospective analysis, the novel indicator prostate specific antigen) (PSA _postd3/PSA_pre, was assessed for its efficacy as a predictor of PSA recurrence in PCa patients who underwent radical prostatectomy (RP). Researchers defined PSA_postd3/PSA_pre as the ratio of the PSA on day 3 postop as the numerator and the pre-operative PSA as the denominator. With a sensitivity of 0.704 and specificity of 0.853, a cut-off at 0.453 was derived by receiver operating characteristic curve for PSA_postd3/PSA_pre, indicating that patients whose PSA on day 3 postop was not reduced to nearly half of their preoperative levels had an increased risk of PSA recurrence. By multivariate logistic regression analysis, a significant relation of only PSA_postd3/PSA_pre, among several factors, to PSA recurrence-free survival was shown. For PSA recurrence prediction in patients following RP, a substantial information could be gained using PSA_postd3/PSA_pre.