Gunasekaran P, et al. - In this retrospective study, researchers evaluated the prognostic importance of high vs low grade coronary artery ectasia (CAE) and the influence of antithrombotic or anticoagulant treatment on adverse cardiac outcomes. All cases of confirmed CAE (2001–2011) were reviewed, focusing on angiograms and medical records. The Markis classification was used to divide the extent of CAE. Types 1 and 2 were classified as high-grade and types 3 and 4 as low-grade CAE. Normal or sluggish (< thrombolysis in myocardial infarction 3) angiographic flow was recorded. Acute coronary syndromes (ACSs) and all-cause death on follow-up were evaluated. In this study, future ACS was independently predicted by angiographic extent of CAE and sluggish coronary flow, despite good medical management. An attenuated risk of future ACS was reported in relation to dual-antiplatelet therapy or oral anticoagulation.