Brescia G, et al. - Researchers conducted this retrospective analysis to newly examine the prognostic role (in terms of recurrence rate) of preoperative blood eosinophil and basophil levels in allergic fungal rhinosinusitis (AFRS). A consecutive series of 17 adult patients who had endoscopic sinus surgery for AFRS were included in this investigation. In 7 of 17 individuals, sinonasal polyps recurred. Considering the present challenge of defining more efficient, personalized solutions to postoperative disease management in AFRS, the preliminary information support the idea that eosinophil and basophil levels warrant testing in further prospective and larger (preferably multi-institutional) investigations as part of the preoperative work-up for patients with AFRS to administer dedicated postoperative medical treatments for patients at higher risk of relapse.