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Prognostic indicators of new onset atrial fibrillation in patients with acute coronary syndrome

Clinical Cardiology Apr 18, 2020

Zhang H, Dong P, Yang X, et al. - Prognostic indicators of new onset atrial fibrillation (AF) in cases with acute coronary syndrome (ACS) were investigated through 3 to 5 years of follow‐up. A collaborative initiative of the American Heart Association and Chinese Society of Cardiology launched the Improving Care for Cardiovascular Disease in China‐ACS (CCC‐ACS) program in 2014. Researchers studied a total of 743 ACS patients. AF developed in 50 (0.67%) patients after 3 to 5 years. NT‐proBNP, creatine kinase‐MB (CK‐MB), and left ventricular ejection fraction were noted to have a considerable prognostic value for predicting whether patients with ACS would develop AF during follow‐up. A cutoff level for AF screening was determined using receiver operating characteristic curves. Using a cutoff of 1,705 ng/L for NT‐proBNP, a sensitivity of 58% and a specificity of 89.8% were attained. Using a cutoff of 142.5 ng/L for CK‐MB, a sensitivity of 73.3% and a specificity of 58.3% were attained. .

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