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Prognostic importance of increased right ventricular afterload in orthotopic liver transplantation recipients with endstage cirrhosis

Heart, Lung, and Circulation May 16, 2018

Couperus LE, et al. - Researchers determined the impacts of mildly increased right ventricular (RV) afterload on long-term outcome after orthotopic liver transplantation (OLT) in relation to RV function. Preoperative RV afterload in subjects was assessed and categorized as normal, high-normal (mean pulmonary artery pressure [PAP] 20–25 mmHg or echocardiographic systolic PAP 35–40 mmHg) or mildly elevated (mean PAP 25–35 mmHg or systolic PAP 40–50 mmHg). Increased RV afterload was found to be related to increased haemodynamic complications and worse long-term survival in OLT recipients. In patients with increased RV afterload, the observed right ventricular function was within normal range and showed no relation to postoperative outcome.
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