Almangush A, et al. - Researchers undertook a multi-institutional study evaluating the prognostic value of tumour–stroma ratio (TSR) from original haematoxylin and eosin (HE)-stained tumour-resection slides in a series of early-stage (cT1-2N0) Oral tongue squamous cell carcinoma (OTSCC) patients. They used a TSR cutoff value of 50% to divide the patients into stroma-rich (≥50%) and stroma-poor (<50%) groups. They identified TSR to be a simple histopathological feature that has value for prognostication of early-stage OTSCC, and suggest that TSR analyses in association with BD score could be included in routine clinical pathology reports for HE-stained slides.