Paternostro R, Bardach C, Hofer BS, et al. - The present study was performed to evaluate the prognostic effect of sarcopenia in cirrhotic patients stratified by different severity of portal hypertension. Researchers included consecutive patients with advanced chronic liver disease (ACLD) and hepatic venous pressure gradient (HVPG) ≥ 10mmHg with available CT/MRI imaging. During follow‐up, hepatic decompensation and mortality were recorded. Sarcopenia was found in 77 (37.9%) and HVPG was ≥ 20mmHg in 98 (48.3%) among 203 patients (68% male, age:55±11, MELD:12[9‐15]). The data exhibited that both in compensated and in decompensated ACLD patients, sarcopenia has a major effect on clinical outcomes. The findings revealed that the presence of sarcopenia doubled the risk for mortality independently from the severity of portal hypertension.