Shinoda Y, Kobayashi E, Kobayashi H, et al. - Given that myxoid liposarcoma (MLS) tends to metastasize extrapulmonary, researchers undertook this retrospective observational study to determine the prognostic factors for disease-specific survival at the initial diagnosis of metastasis. This analysis was performed at three cancer centers and two university hospitals in Japan. Experts analyzed 48 metastatic patients out of 274 MLS patients pathologically diagnosed between 2001 and 2015. Patients with lung metastases vs without were found to have significantly shorter interval from primary diagnosis to the first metastasis. Liver metastasis and no evidence of disease (NED) attained by radical treatment or semi-radical treatment were identified to be significantly associated with survival, as shown in multivariable analysis. Overall, for the first time, it was statistically shown that achieving NED with surgical resection or radiation therapy is important for longer survival in metastatic MLS patients. It might be essential to early detect metastases because number of metastases was identified as a significant factor for achieving NED.