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Prognostic factors of lung adenocarcinoma manifesting as ground glass nodules larger than 3 cm

European Journal of Cardio-Thoracic Surgery Dec 21, 2018

Ding H, et al. - Researchers investigated the prognostic factors of lung adenocarcinomas manifesting as ground glass nodules larger than 3 cm on thin-section computed tomography scans, especially comparing the prognostic role of the whole size and the solid size. Analyzing 195 patients with lung adenocarcinomas manifesting as ground glass nodules larger than 3 cm who underwent surgical resection, they noted solid size as a better predictor of lymph node metastases and prognosis than the whole size in ground glass nodules larger than 3 cm. Hence they recommend considering the solid size rather than the whole size of these lesions in clinical T staging. Adjuvant chemotherapy was noted enhancing survival of patients with stage Ib and II–IIIa disease, but not of patients with stage Ia disease.
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