Oudelaar BW, et al. - A prospective cohort study was performed to assess prognostic factors for the effectiveness of needle aspiration of calcific deposits (NACD) for rotator cuff calcific tendinitis (RCCT). A total of 149 individuals with symptomatic RCCT were included. This study measured pain (VAS), shoulder function (SST and DASH), and quality of life (EQ-5D) at baseline and at 3, 6, and 12 months post-NACD. The carried out univariate analyses (independent t-tests or Mann-Whitney U tests depending on the distribution of data)to build a multivariable linear regression model. They conducted stepwise regression analysis through backward elimination to estimate the impact of predefined prognostic factors on the outcome. At 12 months, good initial response after NACD is correlated with better outcomes. It was noted that individuals with a longer duration of symptoms prior to NACD and patients who require multiple procedures revealed inferior outcomes in terms of pain reduction and enhancement of quality of life. It was demonstrated that smaller-size calcific deposits are correlated with a less favorable result of shoulder function and quality of life scores and might therefore be less susceptible for NACD.