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Prognostic factors for survival and nonfunctional larynx in patients with squamous cell carcinoma of the larynx

The Laryngoscope Jul 05, 2019

Nachalon Y, et al. - In patients with laryngeal squamous cell carcinoma (SCC), researchers assessed prognostic factors for survival and nonfunctional larynx. For this retrospective chart review, they reviewed all patients diagnosed as having laryngeal SCC from January 2007 through December 2016 in a tertiary, university-affiliated medical center. Participants in the study were 265 patients. Data reported that overall and disease-free survival were 7.9 and 6.7 years, respectively. In larynx cancer patients, older age, history of alcohol use, and advanced disease stage at presentation negatively affect survival. Investigators found that male gender and advanced disease stage raised the risk, and anterior commissure involvement was found to lessen the risk for tracheostomy or feeding-tube dependency.
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