Blackburn BE, et al. - Researchers examined a population-based cohort to compare prognostic factors between rural endometrial cancer patients and urban patients. They used the Utah Cancer Registry and Utah Population Database and identified 2,994 endometrial cancer patients, rural patients constituted 14.1% of overall study sample. Older age at cancer diagnosis was noted in rural endometrial cancer patients. In terms of obesity or overweight at cancer diagnosis, there seemed no difference between the two populations. Also, no differences were found for treatment or stage at diagnosis although higher proportions of higher grade were reported in rural patients. Important prognostic factors for all-cause mortality were age at diagnosis, poverty, education, and histology. The risks of all-cause and endometrial cancer-specific death were significantly higher in rural patients with more advanced stages of cancer vs urban patients. Findings revealed a 17-fold rise in the risk of all-cause death in rural endometrial cancer patients diagnosed at advanced stage vs an 8-fold increase in mortality in urban patients.