Prognostic factors and scoring model of hematological malignancies patients with bloodstream infections
Infection May 20, 2018
Tang Y, et al. - Researchers developed and validated a reliable prediction model which can be used to identify hematological malignancy (HM) patients at higher risk for bloodstream infections (BSIs). Among a total of 521 analyzed HM patients, survivors and non-survivors were compared to identify the predictors of 30-day mortality. Significant mortality-related risk factors identified were age>60 years, relapsed or uncontrolled malignancy, Pitt bacteremia score>3, prolonged neutropenia, use of vasopressors, acute respiratory failure, fungemia, inadequate antibiotic treatment, albumin < 30 g/L, TBil>34.2 μmol/L. These risk factors were noted to have the ability to identify patients with HMs and BSIs at high risk for mortality. In HM patients suffering from BSI, the developed model provides an excellent foundation for predicting 30-day morality and helps target high-risk patients for management decision making.
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