Lu T, et al. - In this retrospective analysis involving 19 patients, researchers examined the prognosis of reduced-dose radiation in nasopharyngeal carcinoma (NPC) adult. Participants in the study were patients histologically diagnosed with NPC, who received <66 Gy radiation therapy. Ten patients receiving <54 Gy to the primary site were group A and 9 patients receiving ≥54 Gy were group B. Thirteen patients got two or three cycles of induction chemotherapy (IC). The 5-year overall survival was 50.0% in group A. For group B, the 5-year overall survival, locoregional relapse-free survival, progression-free survival, and distant metastasis-free survival were 88.9%, 100.0%, 88.9%, and 88.9%. Group B had a stronger forecast on the overall survival than group A. The authors concluded that patients who received ≥54 Gy but <66 Gy with IC attained good local control and long-term survival.