Alazmi M, et al. - This inquiry was set up to assess the factors associated with TNF inhibitory (TNFi) failure types and their characteristics in axial spondyloarthritis (AxSpA). Nearly 40% of the TNFi failures in AxSpA patients were attributed to primary lack of response, which was independently predicted by older age, negative HLA-B27, higher baseline disease activity and treatment with sTNFR.