Profiles of pro-inflammatory cytokines in allogenic stem cell transplantation with post-transplant cyclophosphamide
Cytokine Sep 19, 2017
Pirogova OV, et al. - Aim was to illustrate the profiles of pro-inflammatory cytokines in allogenic stem cell transplantation with post-transplant cyclophosphamide (PTCy). In this study, the levels of IL-17, IL-6, IL-8, IFN-γ and TNF-α in plasma on days -7, 0, +7, +14 and after engraftment in 20 patients with acute graft-versus-host disease (GVHD) and 40 matched control patients with PTCy-based prophylaxis were computed. After conventional prophylaxis, the dynamics of IL-8 and IFN-γ in GVHD patients after PTCy was different from previously reported.
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