Zhao Y, Peng H, Li X, et al. - Researchers assessed the effect of dissection and reentry (DR) techniques vs wire escalation (WE) techniques on periprocedural results in patients with chronic total occlusion (CTO) receiving percutaneous coronary intervention (PCI), via this meta-analysis of relevant studies identified from electronic database from inception to December 2018. Random effects model and fixed effects model were used to pool results. Findings revealed a relatively frequent use of DR technique during contemporary CTO PCI, particularly for challenging more complex CTO lesions. However, in comparison with a conventional WE strategy, the DR technique was found to be related to higher, yet acceptable, rates of periprocedural adverse events. To define the optimal role of DR in hybrid CTO PCI, further refinement of DR techniques as well as evidence from large RCTs is required.