Nielsen MJ, Baines P, Jennings R, et al. - Researchers evaluated diagnostic accuracy of procalcitonin (PCT), neutrophil gelatinase-associated lipocalin (NGAL), resistin, activated partial thromboplastin time (aPTT) waveform and C-reactive protein (CRP) for serious bacterial infection (SBI) in children on admission to PICU. In addition, they examined their use as prognostic indicators. They obtained blood samples daily for biomarker measurement. Among a total of 657 patients included in the study, criteria for SBI were fulfilled by 92 patients (14%). Twenty-eight day mortality of 2.6% (17/657) was observed, but for patients with SBI, it was 8.7% (8/92). Accurate and timely identification of SBI on admission to PICU may improve with combining biomarkers, including PCT.