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Procalcitonin and presepsin as prognostic markers after out-of-hospital cardiac arrest

Shock Sep 25, 2018

Pekkarinen PT, et al. – Researchers investigated whether procalcitonin and presepsin could provide information regarding the severity of post-cardiac arrest syndrome and whether these biomarkers could predict short-term hemodynamical instability and long-term neurological outcome after cardiac arrest in this subcohort analysis of a prospective, observational, multicenter study. Participants included 277 intensive care unit patients treated following out-of-hospital cardiac arrest (OHCA). Findings showed an association of elevated procalcitonin with hemodynamical instability and worsened long-term outcome in OHCA patients; however, was not strong enough to be used as a single predictor. Presepsin did not provide clinically relevant information for risk stratification following OHCA.

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