Oh J, et al. - Researchers conducted this retrospective analysis to assess the outcomes of organ preservation and laryngectomy for T4a laryngeal cancer. Participants in the study were patients with T4a larynx cancer at BC Cancer from 1984 to 2014. For this investigation, they compared outcomes in patients treated with surgery alone (Sx) (n=47), surgery with adjuvant radiotherapy (Sx/RT) (n=94), radiation alone (RT) (n=152), and radiation with concurrent chemoradiotherapy (chemoRT) (n=36). Data reported that the 5-year overall survival (OS) was 40% for chemoRT, 34% for RT, 23% for Sx, and 45% for Sx/RT. Compared with single modality treatment, ChemoRT and Sx/RT were linked to a better OS. Findings suggested that ChemoRT can be regarded as an option for T4a larynx cancer.