Li Y, et al. - Researchers intended to discern the efficacy and rationality of primary antifungal prophylaxis (PAP) in a 5-year real-life scenario and chose an appropriate PAP strategy. A requirement arose for primary antifungal prophylaxis. It appeared to be efficient to prevent invasive fungal disease (IFD) in hematological patients. The real-life PAP strategy was determined to be reasonable. Findings revealed that different drugs could be chosen. Experts recommended the start of PAP as soon as neutropenia began.