Jozwiak S, Słowińska M, Borkowska J, et al. - In children with tuberous sclerosis complex who received preventive antiepileptic treatment in infancy, researchers conducted this prospective, non-randomized clinical trial to assess the neuropsychologic and epilepsy outcomes at school age. The study sample consisted of 14 infants with tuberous sclerosis complex in whom serial electroencephalographic recordings were conducted, and preventive treatment with vigabatrin was initiated when active epileptic discharges were identified. For the preventive group, the median intelligence quotient was 94 vs 46 for the standard group. This research offers proof that in infants with tuberous sclerosis complex, preventive antiepileptic therapy may improve control of long-term epilepsy and cognitive outcome at school age.