Salzer J, et al. - Researchers investigated patients [n = 952; mean (SD) age was 51.1 (16.7) years] undergoing diagnostic lumbar puncture (LP) to study the impacts of needle size, needle design and stylet reinsertion on the risk for postdural puncture headache (PDPH). This investigation was conducted at Umeå University Hospital in Sweden during 2013–2018. Participants in the study were randomly assigned one of three needles (22 Gauge (G) atraumatic, 25G atraumatic and 25G cutting); and stylet reinsertion before needle withdrawal or not. According to this randomized double-blind study, a 25G atraumatic needle is better than a larger atraumatic needle and a cutting needle of the same size to avoid PDPH following the diagnosis of LP. This research did not find that stylet reinsertion was successful to prevent PDPH, as opposed to one earlier report.