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Prevalence, treatment, and outcomes of coexistent pulmonary hypertension and interstitial lung disease in systemic sclerosis

Arthritis & Rheumatology Jun 27, 2019

Young A, et al. - Via a prospective observational cohort study on 93 patients with Systemic sclerosis (SSc)-associated interstitial lung disease (ILD) on high-resolution computed tomography, the researchers intended to discover the prevalence, characteristics, treatment, and outcomes of pulmonary hypertension (PH). Right-sided heart catheterization-proven PH was observed in 29 patients. The survival rate was 97% at 3 years after SSc-associated ILD diagnosis for all patients whereas, the survival rate at 3 years post-PH diagnosis for those with SSc-associated ILD and PH was 91%. Hence, coexisting PH, which often occurs early after SSc diagnosis, was observed in a significant proportion of patients. The survival rate of the patients who were treated with ILD and PAH therapies were good. Further, or coexisting PH, patients with SSc-associated ILD should be assessed.
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