Valderrama-Hinds LM, García-Carrión E, Hernández E, et al. - Via a cross-sectional study of 92 consecutive individuals with Hashimoto thyroiditis (HT) and no definite rheumatic disease from the Endocrinology Division, Hospital Universitario de Caracas diagnosed by the presence of anti-thyroid peroxidase antibodies (n = 68) or typical ultrasonographic findings (n = 24), experts authenticated the predominance of undifferentiated inflammatory arthropathy (UIA) in unselected HT patients as noticed in an endocrinology clinic. For UIA, 23 patients met the criteria. Most generally affected joints were the knees, hands, and ankles and the most prevalent pattern was oligoarticular. In the multivariate analysis, the presence of myalgia and Raynaud's phenomenon were variables related to the presence of UIA. No relationship was discovered with demographics, the term of disease, comorbidities or thyroid function status. In conclusion, almost one in four cases with HT had no particular rheumatic disease present with UIA. To prevent potential joint damage and disability, for thorough differential diagnosis and immediate treatment beginning, early detection of concurrent arthritis in HT cases is required.