Prevalence of thyroid dysfunction in postpartum women with suboptimal iodine and selenium and adequate iron status
Clinical Endocrinology May 28, 2021
Jin Y, Coad J, Zhou, et al. - The present study was performed to explore thyroid dysfunction within a cohort of women at six months postpartum in relation to iodine, selenium, and iron status. This cross-sectional study was part of an observational longitudinal cohort Mother and Infant Nutrition Investigation; data obtained at six months postpartum are reported. Researchers conducted a cross-sectional study including 87 mother-infant pairs at three months postpartum and followed up at six months postpartum. They assessed thyroid hormones (free triiodothyronine, free thyroxine, thyroid-stimulating hormone) and thyroid peroxidase antibodies. They further ascertained urinary iodine concentration, breast milk iodine concentration, serum thyroglobulin, plasma selenium, serum ferritin, and serum soluble transferrin receptors. A high prevalence of thyroid dysfunction was found. It was shown that plasma selenium concentration was the only significant predictor of the likelihood that women had thyroid dysfunction within this cohort, who were iodine deficient and mostly had adequate iron status. There is a need for strategies to improve both iodine and selenium status to better support maternal thyroid function.
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