Pados G, et al. – This study was performed to examine the prevalence of leiomyosarcomas and atypical leiomyomas after laparoscopic morcellation of fibroids in reproductive age women. According to the outcome obtained, no case of leiomyosarcomas was seen but they found seven atypical leiomyomas in 1216 subjects.

Methods

• For this study, they conducted a retrospective review.
• In this study, they reviewed the data extracted from a single center database of 1216 consecutive women who underwent laparoscopic morcellation of 2582 unsuspicious leiomyomas between June 2003 and December 2015 and were followed–up until December 2016.
• A total of 1216 women, aged 18–45 years, underwent laparoscopic morcellation of 2582 apparently benign leiomyomas by the same surgeon and all specimen slides were analyzed by the same experienced pathologist.

Results

• In this study, they found the prevalence of leiomyosarcomas and atypical leiomyomas was 0% (95% CI: 0–0.3%) and 0.6% (95% CI: 0.23–1.18%) (six atypical–bizarre and one mitotically active leiomyoma) respectively.
• In addition, there were recognized 34 cases of adenomyomas, 45 leiomyomas with infarcts, 81 cellular leiomyomas and 133 degenerated leiomyomas.
• There was no recorded morcellator– related complication and none of the patients included in this study required conversion to laparotomy.