Prevalence of chronic rhinosinusitis in bronchiectasis patients suspected of ciliary dyskinesia
International Forum of Allergy & Rhinology Aug 25, 2019
McCormick JP, Weeks CG, Rivers NJ, et al. - In bronchiectasis patients suspected of harboring ciliary dyskinesia, researchers assessed the prevalence of chronic rhinosinusitis (CRS) and its characteristics. Participants in the study were bronchiectasis patients referred to a rhinology clinic for nasal brush biopsy (NBB). Between 2015 and 2018, 23 patients (age, 54 ± 2.9 years) were referred for NBB. Thirteen patients met CRS diagnostic criteria. Compound cilia were the most common finding. Nearly half of NBB-referred bronchiectasis patients had CRS at the same time. Compared with those without CRS, the presence of ciliary abnormalities was not amplified in bronchiectasis patients with CRS. Extrinsic factors in non-primary ciliary dyskinesia gene carriers may be associated with ciliary structural defects.
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