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Prevalence of biochemical osteomalacia in adults undergoing vitamin D testing

Clinical Endocrinology Apr 22, 2021

Bolland MJ, et al. - Researchers conducted the study for examining the prevalence of biochemical osteomalacia in adults with a measurement of 25‐hydroxyvitamin D (25OHD). 25OHD results between January 1, 2009, and June 15, 2020, were collected from the regional laboratory database, together with measurements of serum calcium, parathyroid hormone (PTH) and alkaline phosphatase (ALP) within 6 months of the index 25OHD. Over the 11.5y period, 110,046 25OHD measurements were identified. After removal of ineligible measurements, 42,171 25OHD measurements from 32,386 people with at least 2 of aCa, PTH, and ALP were involved in analyses. Even in individuals with 25OHD < 25 nmol/L, the prevalence of biochemical osteomalacia is very low.

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