Eaton JL, et al. - In this retrospective national study, researchers contrasted the odds of a good perinatal outcome between cryopreserved and fresh donor oocytes. To conduct a retrospective cohort study of women undergoing donor oocyte in vitro fertilization (IVF) from 2012 to 2015, they used the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System. Of the analyzed 36,925 cycles, 8,381 used cryopreserved and 28,544 used fresh oocytes. Cryopreserved oocytes were linked to lower rates of live birth, multiple birth, and prematurity compared with fresh oocytes. According to findings, the use of cryopreserved vs fresh donor oocytes in IVF cycles was related to marginally lower odds of a good perinatal outcome.