Siddiqui MS, et al. - Among caregivers of patients with nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease, affecting nearly 1 in 3 Americans, cirrhosis, researchers determined the prevalence and severity of NAFLD. In this investigation, researchers tested the premise that patients with nonalcoholic steatohepatitis (NASH) cirrhosis reside in a microenvironment conducive to not only development of NASH but also fibrosis progression, which likely persist after liver transplantation (LT) and contribute to disease recurrence. The hypothesis was tested in primary caregivers and cohabitants of patients with decompensated cirrhosis waiting for LT by vibration- controlled transient elastography (VCTE). Investigators observed that NASH-related cirrhosis is now the most rapidly growing indication for LT. Disease recurrence and progression to advanced fibrosis after LT are high. However, the key contributors of these are unknown.